The Cabinet of the Republic of Kenya is made up of the President, Deputy President, Attorney General, and Cabinet Secretaries. The 2010 Constitution of Kenya allows a maximum of 22 ministries under Article 152 and sets the minimum number to 14. A Cabinet Secretary is not a member of the Kenyan Parliament and has to be vetted by a parliamentary committee before their appointment. Cabinet secretaries head and manage their respective ministries per the Constitution of Kenya.
Here are the cabinet secretaries in Kenya.
| No. | Ministry | Cabinet Secretary |
| 1. | Prime Cabinet Secretary and Cabinet Secretary for Foreign and Diaspora Affairs | Wycliffe Musalia Mudavadi |
| 2. | Interior and National Administration | Onesimus Kipchumba Murkomen |
| 3. | Roads and Transport | Davis Chirchir |
| 4. | Mining, Blue Economy and Maritime Affairs | Hassan Ali Joho |
| 5. | Health | Aden Duale |
| 6. | Lands, Public Works, Housing and Urban Development | Alice Wahome |
| 7. | Labour and Social Protection | Dr. Alfred Mutua |
| 8. | Education | Julius Migos Ogamba |
| 9. | Tourism and Wildlife | Rebecca Miano |
| 10. | Youth Affairs, Creative Economy and Sports | Salim Mvurya |
| 11. | Defence | Roselinda Soipan Tuya |
| 12. | Co-operatives and Micro Small and Medium Enterprises (MSMEs) Development | Wycliffe Ambetsa Oparanya |
| 13. | National Treasury and Economic Planning | Salim Mvurya |
| 14. | Water, Sanitation and Irrigation | Davis Chirchir |
| 15. | Environment, Climate Change & Forestry | Franklin Mithika Linturi |
| 16. | Investments, Trade and Industry | Peninah Malonza |
| 17. | Agriculture and Livestock Development | Aisha Jumwa Karisa Katana |
| 18. | Energy and Petroleum | Prof. Njuguna Ndung’u |
| 19. | Information Communication and the Digital Economy | Florence Bore |
| 20. | Public Service and Human Capital Development | Aden Bare Duale |
| 21. | East Africa Community and Regional Affairs | Beatrice Asukul Moe |
| 22. | Gender | Hanna Wendot Cheptumo |
| Other cabinet appointments | ||
| No. | Office | Holder |
| 1. | Attorney General of Kenya | Dorcas Agik Oduor |
| 2. | Secretary to the Cabinet | Mercy Kiiru Wanjau |
| 3. | National Security Advisor | – |
